MARC状态:待编 文献类型:西文图书 浏览次数:2
- 题名/责任者:
- Integrated Structural Biology
- 出版发行项:
- Royal Society Of Chemistry 2023.
- ISBN:
- 9781839161834
- 载体形态项:
- 386 p..
- 变异题名:
- 综合结构生物学
- 丛编说明:
- New Developments In Nmr
- 论题主题:
- Magnetic resonance
- 中图法分类号:
- Q81
- 摘要附注:
- Modern research in biology increasingly relies on multiple techniques for describing structures and mechanisms. This book provides an overview of the contemporary integrated biology approaches for solving structures and understanding mechanisms of complex biological systems. It includes several methodology chapters discussing the current developments in the areas of cryo-electron microscopy (EM) and cryo-electron tomography (ET), computational biophysics, solution NMR spectroscopy, solid-state NMR spectroscopy and dynamic nuclear polarization (DNP), electron paramagnetic resonance (EPR), (photo-)chemically induced dynamic nuclear polarization (CIDNP), X-ray crystallography and small-angle X-ray and neutron scattering (SAXS/SANS). Several subsequent chapters demonstrate how these methods are used in synergy to address problems at the forefront of structural biology, with particular emphasis on examples where individual techniques are insufficient. Examples of biological systems include membrane proteins, viral protein assemblies, cytoskeleton protein assemblies, photosynthetic reaction centers, large enzyme complexes and whole cells.
- 随书光盘:
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