MARC状态：审校 文献类型：西文图书 浏览次数：82
- 题名/责任者:
- Applications of toxicogenomics in safety evaluation and risk assessment / edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.
- 出版发行项:
- Hoboken, N.J. : John Wiley & Sons, c2011.
- ISBN:
- 9780470449820 (cloth) :
- ISBN:
- 9781118001042 (oBook)
- ISBN:
- 9781118001035 (ePDF)
- ISBN:
- 9781118008980 (ePub)
- 载体形态项:
- xiii, 377 p., [8] p. of plates : ill. (some col.) ; 25 cm.
- 附加个人名称:
- Boverhof, Darrell R.
- 附加个人名称:
- Gollapudi, B. Bhaskar.
- 论题主题:
- Genetic toxicology.
- 论题主题:
- Toxicity testing.
- 论题主题:
- Health risk assessment.
- 论题主题:
- Toxicogenetics.
- 论题主题:
- Risk Assessment.
- 中图法分类号:
- R99
- 书目附注:
- Includes bibliographical references and index.
- 内容附注:
- Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment -- early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation -- activities in Japan -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.
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