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- 题名/责任者:
- Programmed cell death : the biology and therapeutic implications of cell death. Part B / edited by Roya Khosravi-Far ... [et al.]
- 出版发行项:
- Amsterdam ; Boston : Elsevier, c2008.
- ISBN:
- 0123744644 (pt. B)
- ISBN:
- 9780123744647 (pt. B) :
- 载体形态项:
- xlviii, 450 p., [6] p. of plates : ill. (some col.) ; 24 cm.
- 丛编题名:
- Methods in enzymology ; v. 446
- 附加个人名称:
- Khosravi-Far, Roya.
- 论题主题:
- Cancer cells-Variation.
- 论题主题:
- Apoptosis.
- 论题主题:
- Cell death.
- 中图法分类号:
- Q55-5
- 中图法分类号:
- Q255
- 书目附注:
- Includes bibliographical references and indexes.
- 内容附注:
- 1. Analysis of autophagic and necrotic cell death in dictyostelium -- 2. Methods and protcols for studying cell death in drosophila -- 3. In vivo and in vitro methods for studying apoptotic cell engulfment in drosophila -- 4. Mouse mammary epithelial cell model to identify molecular mechanisms in regulating breast cancer progression -- 5. Immortalized mouse epithelial cell models to study the role of apoptosis in cancer -- 6. DNA damage response and apoptosis -- 7. Phorbol ester-induced apoptosis and senescence in cancer cell models -- 8. Manipulation of PKC isozymes by RNA interference and inducible expression of PKC constructs -- 9. Studying p53-dependent cell death in vitro and in vivo -- 10. NF-kB as a determinant of distinct cell death pathways -- 11. Purification and bioassay of hedgehog ligands for the study of cell death and survival -- 12. Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis -- 13. Ubiquitination mediated by inhibitor of apoptosis proteins -- 14. Phospatases and regulation of cell death -- 15. Analysis of neuronal cell death in mammals -- 16. Dissecting apoptosis and intrinsic death pathways in the heart -- 17. Quantification of vascular endothelial cell apoptosis in vivo -- 18. Recombinant TRAIL and TRAIL receptor analysis -- 19. Analysis of Tnf-related apoptosis-inducing ligand in vivo through bone marrow transduction and transplantation -- 20. Overcoming resistance to TRAIL-induced apoptosis in prostate cancer by regulation of c-FLIP -- 21. Caspase assays: Identifying caspase activity and substrates in vitro and in vivo -- 22. Synthesis and biophysical characterization of stabilized a-helices of BCL-2 domains -- 23. Dissection of the BCL-2 family signaling network with stabilized x-helices of BCL-2 domains -- 24. ERM-mediated genetic screens in mammalian cells.
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