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- 题名/责任者:
- Gene transfer vectors for clinical application / edited by Theodore Friedman.
- 出版发行项:
- Amsterdam, Netherlands ; Boston, Mass. : Elsevier/Academic Press, c2012.
- ISBN:
- 9780123865090 :
- ISBN:
- 0123865093
- 载体形态项:
- l, 385 p., [14] p. of plates : ill. (some col.) ; 24 cm.
- 丛编说明:
- Methods in enzymology ; v. 507
- 附加个人名称:
- Friedmann, Theodore, 1935-
- 论题主题:
- Gene therapy.
- 论题主题:
- Genetic vectors.
- 论题主题:
- Genetic transformation.
- 中图法分类号:
- Q55-5
- 中图法分类号:
- Q34
- 书目附注:
- Includes bibliographical references and indexes.
- 内容附注:
- General principles of retrovirus vector design -- Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) -- Retrovirus and lentivirus vector design and methods of cell conditioning -- Analysis of the clonal repertoire of gene-corrected cells in gene therapy -- Developing novel lentiviral vectors into clinical products -- Lentivirus vectors in b-thalassemia -- Gene therapy for chronic granulomatous disease -- Alternative splicing caused by lentiviral integration in the human genome -- Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- mice -- Lentiviral hematopoietic cell gene therapy for x-linked adrenoleukodystrophy -- Retroviral replicating vectors in cancer -- Adeno-associated virus vectorology, manufacturing, and clinical applications -- Gene delivery to the retina: from mouse to man -- Generation of hairpin-based RNAi vectors for biological and therapeutic application -- Recombinant adeno-associated viral vector reference standards -- NIH oversight of human gene transfer research involving retroviral, lentiviral, and adeno-associated virus vectors and the role of the NIH Recombinant DNA Advisory Committee -- Regulatory structures for gene therapy medicinal products in the European Union.
- 随书光盘:
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