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• 005 20130917151500.0

• 008 100106s2010 enka b 001 0 eng

• 010 __ |a 2010000254

• 020 __ |a 9780470519745 (cloth) : |c CNY1251.00

• 040 __ |a DNLM/DLC |c DLC |d YDX |d NLM |d UKM |d YDXCP |d CDX |d BWX |d SCT

• 042 __ |a pcc

• 050 00 |a QP620 |b .C44

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• 090 __ |a Q52/CBN/ED-11

• 093 __ |a Q52 |2 4

• 099 __ |a CAL 022010221069

• 245 04 |a The chemical biology of nucleic acids / |c edited by Günter Mayer.

• 260 __ |a Chichester, UK : |b Wiley, |c 2010.

• 300 __ |a xiii, 464 p., [16] p. of plates : |b ill. ; |c 26 cm.

• 504 __ |a Includes bibliographical references and index

• 505 0_ |a Chemical synthesis of modified RNA / Claudia Höbartner and Falk Wachowius -- Expansion of the genetic alphabet in nucleic acids by creating new base pairs / Ichiro Hirao and Michiko Kimoto -- Chemical biology of DNA replication : probing DNA polymerase selectivity mechanisms with modified nucleotides / Andreas Marx -- Nucleic-acid-templated chemistry / Michael Oberhuber -- Chemical biology of peptide nucleic acids (PNA) / Peter E. Nielsen -- The interactions of small molecules with DNA and RNA / Yun Xie, Victor Tam and Yitzhak Tor -- The architectural modules of folded RNAs / V. Fritsch and Eric Westhof -- Genesis and biological applications of locked nucleic acid (LNA) / Harleen Kaur and Souvik Maiti -- Small non-coding RNA in bacteria / Sabine Brantl -- Microrna-guided gene silencing / Gunter Meister -- Nucleic acids based therapies / Britta Hoehn and John J. Rossi -- Innate immune recognition of nucleic acid / Stefan Bauer -- Light-responsive nucleic acids for the spatiotemporal control of biological processes / Alexander Heckel and Günter Mayer -- DNA methylation / Albert Jeltsch and Renata Z. Jurkowska -- Frameworks for programming RNA devices / Maung Nyan Win, Joe C. Liang and Christina D. Smolke -- RNA as a catalyst : the Diels-Alderase-ribozyme / Andres Jäschke -- Evolving an understanding of RNA function by in vitro approaches / Qing Wang and Peter J. Unrau -- The chemical biology of aptamers : synthesis and applications / Günter Mayer & Bernhard Wulffen -- Nucleic acids as detection tools / Jeffrey C.F. Lam, Sergio Aguirre and Yingfu Li -- Bacterial riboswitch discovery and analysis / Tyler D. Ames and Ronald R. Breaker

• 650 _0 |a Nucleic acids.

• 650 12 |a Nucleic Acids |x chemistry.

• 650 22 |a Nucleic Acids |x physiology.

• 650 22 |a Nucleic Acids |x therapeutic use.

• 700 1_ |a Mayer, Günter, |d 1972-

• 920 __ |a 211180 |z 2