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• 000 01751nam a2200205 450

• 001 0000627603

• 005 20241012132826.914

• 008 241012c2024

• 020 __ |a 9783031688102 |b Hardback |c EUR179.99

• 040 __ |a CEPIEC |b CEPIEC

• 041 __ |a ENG

• 093 __ |a Q2

• 100 1_ |a Kirsi Rilla.

• 245 __ |a Extracellular Vesicles As Matrix Messengers

• 246 __ |a 细胞外囊泡基质信使

• 260 __ |b Springer |c 2024.

• 300 __ |a 314 p..

• 490 __ |a Biology Of Extracellular Matrix |b 15.

• 520 __ |a The cells in our body release a wide variety of factors into the extracellular space that help to signal, regulate and build the extracellular matrix. One of the most fascinating of these factors are extracellular vesicles (EVs). These lipid membrane-covered particles have now emerged as a new powerful method of near and distant intercellular communication. EVs facilitate communication between cells and their extracellular environment, which includes solid tissues and body fluids. This volume summarizes current knowledge on EVs as integral and active components of the extracellular matrix. It covers topics such as the interplay between EVs and ECM molecules and how cancer cells modify their microenvironment by releasing EVs. Additionally, it discusses how EVs can mediate tissue repair and regeneration by modulating matrix degradation, protein cross-linking, and matrix calcification. The book explores instances where EVs play a crucial role in conditions related to matrix biology, such as cancer and arthritis, and considers their potential as therapeutic agents for these medical conditions.

• 650 __ |a Biomedical and life sciences / membrane trafficking / cell biology / mechanisms of disease / regenerative medicine and tissue engineering / biotechnology