机读格式显示(MARC)
- 000 02208cam a2200289 a 4500
- 008 120314s2012 ne a b 001 0 eng d
- 020 __ |a 9780123865090 : |c CNY1000.00
- 040 __ |a LHL |c LHL |d AAA |d DNU
- 050 _4 |a QP601 |b .C733 v.5
- 099 __ |a CAL 022012087197
- 245 00 |a Gene transfer vectors for clinical application / |c edited by Theodore Friedman.
- 260 __ |a Amsterdam, Netherlands ; |a Boston, Mass. : |b Elsevier/Academic Press, |c c2012.
- 300 __ |a l, 385 p., [14] p. of plates : |b ill. (some col.) ; |c 24 cm.
- 490 0_ |a Methods in enzymology ; |v v. 507
- 504 __ |a Includes bibliographical references and indexes.
- 505 0_ |a General principles of retrovirus vector design -- Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) -- Retrovirus and lentivirus vector design and methods of cell conditioning -- Analysis of the clonal repertoire of gene-corrected cells in gene therapy -- Developing novel lentiviral vectors into clinical products -- Lentivirus vectors in b-thalassemia -- Gene therapy for chronic granulomatous disease -- Alternative splicing caused by lentiviral integration in the human genome -- Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- mice -- Lentiviral hematopoietic cell gene therapy for x-linked adrenoleukodystrophy -- Retroviral replicating vectors in cancer -- Adeno-associated virus vectorology, manufacturing, and clinical applications -- Gene delivery to the retina: from mouse to man -- Generation of hairpin-based RNAi vectors for biological and therapeutic application -- Recombinant adeno-associated viral vector reference standards -- NIH oversight of human gene transfer research involving retroviral, lentiviral, and adeno-associated virus vectors and the role of the NIH Recombinant DNA Advisory Committee -- Regulatory structures for gene therapy medicinal products in the European Union.
- 650 _0 |a Genetic vectors.
- 650 _0 |a Genetic transformation.
- 700 1_ |a Friedmann, Theodore, |d 1935-