机读格式显示(MARC)

• 000 02493cam a2200385 a 4500

• 000 1000101112

• 001 0000324288

• 005 20090104110220.0

• 008 080512s2008 njua b 001 0 eng

• 020 __ |a 1588296385 (hbk.)

• 020 __ |a 9781603270489 (e-book)

• 020 __ |a 1603270485 (e-book)

• 020 __ |a 9781588296382 (hbk.) : |c CNY896.00

• 040 __ |a UKM |c UKM |d BTCTA |d BAKER |d YDXCP |d CUS |d CDX |d COU |d CHL

• 050 _4 |a QV 38 E78 2008

• 050 _4 |a QH465.C5 |b E87 2008

• 082 04 |a 616.042 |2 22

• 090 __ |a R99/ECT

• 093 __ |a R99 |2 4

• 099 __ |a CAL 022008165566

• 245 00 |a Essential concepts in toxicogenomics / |c edited by Donna L. Mendrick, William B. Mattes.

• 260 __ |a Totowa, N.J. : |b Humana Press ; |a [London : |b Springer, distributor], |c c2008.

• 300 __ |a xi, 277 p., [8] p. of plates : |b ill. (some col.) ; |c 25 cm.

• 440 _0 |a Methods in molecular biology ; |v v. 460

• 504 __ |a Includes bibliographical references and index.

• 505 0_ |a Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge.

• 650 _2 |a Toxicogenetics.

• 650 _0 |a Genetic toxicology.

• 650 _0 |a Genomics.

• 700 1_ |a Mendrick, Donna L.

• 700 1_ |a Mattes, William B.

• 901 __022009000008

• 905 __ |a CAU |f R99/ECT |b W0081587ED-11(or.)

• 907 __ |a CAU |f R99/ECT |b W0081587ED-11(or.)

• 999 __ |I wzhlc |i 20090104 11:02:20 |G wzhlc |g 20090114 17:21:0