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• 008 050623s2006 maua b 001 0 eng

• 010 __ |a 2005018202

• 020 __ |a 1405135441 (pbk. : alk. paper) : |c CNY391.00

• 040 __ |a DNLM/DLC |c DLC |d NLM |d BAKER |d BWKUK |d UKM |d AGL |d DLC

• 042 __ |a pcc

• 050 00 |a QH442 |b .O42 2006

• 060 10 |a QH 442 |b P952pa 2006

• 060 00 |a 2006 H-690

• 082 00 |a 660.6/5 |2 22

• 090 __ |a Q78/PSB:2/(7)

• 093 __ |a Q78 |2 4

• 099 __ |a CAL 022006088149

• 100 1_ |a Primrose, S. B.

• 245 10 |a Principles of gene manipulation and genomics / |c S.B. Primrose and R.M. Twyman.

• 250 __ |a 7th ed.

• 260 __ |a Malden, MA ; |a Oxford : |b Blackwell Publishing, |c 2006.

• 300 __ |a xxii, 644 p. : |b ill. ; |c 28 cm.

• 500 __ |a Rev. ed. of: Principles of gene manipulation. 6th ed. 2001 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman. 3rd ed. 2003.

• 504 __ |a Includes bibliographical references (p. [547]-626) and index.

• 505 0_ |a Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.

• 650 _0 |a Gene mapping.

• 650 _0 |a Nucleotide sequence.

• 650 12 |a Genetic Engineering.

• 650 22 |a Base Sequence.

• 650 22 |a Chromosome Mapping.

• 650 22 |a DNA, Recombinant.

• 650 22 |a Genomics.

• 650 _0 |a Genetic engineering.

• 650 _0 |a Genomics.

• 700 1_ |a Primrose, S. B. |t Principles of genome analysis and genomics.

• 700 1_ |a Twyman, Richard M.

• 700 1_ |a Primrose, S. B. |t Principles of gene manipulation.

• 901 __022006018601

• 905 __ |a CAU |f Q78/PSB:2/(7) |b W0075947ED-11(or.)

• 907 __ |a CAU |f Q78/PSB:2/(7) |b W0075947ED-11(or.)

• 999 __ |I wzhlc |i 20060928 14:07:41 |G wzhlc |g 20060928 14:07:4