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MARC状态:已编 文献类型:西文图书 浏览次数:59

题名/责任者:
Essential concepts in toxicogenomics / edited by Donna L. Mendrick, William B. Mattes.
出版发行项:
Totowa, N.J. : Humana Press ; [London : Springer, distributor], c2008.
ISBN:
1588296385 (hbk.)
ISBN:
9781603270489 (e-book)
ISBN:
1603270485 (e-book)
ISBN:
9781588296382 (hbk.) :
载体形态项:
xi, 277 p., [8] p. of plates : ill. (some col.) ; 25 cm.
丛编题名:
Methods in molecular biology ; v. 460
附加个人名称:
Mendrick, Donna L.
附加个人名称:
Mattes, William B.
论题主题:
Toxicogenetics.
论题主题:
Genetic toxicology.
论题主题:
Genomics.
中图法分类号:
R99
书目附注:
Includes bibliographical references and index.
内容附注:
Toxicogenomics and classical toxicology, how to improve prediction and mechanistic understanding of human toxicity / Donna L. Mendrick -- Use of traditional endpoints and gene dysregulation to understand mechanisms of toxicity / Wayne R. Buck, Jeffrey F. Waring, Eric A. Blomme -- Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications / Karol L. Thompson and Joseph Hackett -- Role of statistics in toxicogenomics / Michael Elashoff -- Predictive toxicogenomics in preclinical discovery / Scott A. Barros and Rory B. Martin -- In vivo predictive toxicogenomics / Mark W. Porter -- Bioinformatics, databasing and gene annotation / Lyle D. Burgoon and Timothy R. Zacharewski -- Microarray probe mapping and annotation in cross - species comparative toxicogenomics / John N Calley, William B Mattes, Timothy P. Ryan -- Toxicogenomics in biomarker discovery -- Marc F. DeCristofaro, Kellye K. Daniels -- From pharmacogenomics to translational biomarkers / Donna L. Mendrick -- Public consortium efforts in toxicogenomics / William B. Mattes -- Applications of toxicogenomics to nonclinical drug development / Frank D. Sistare, Joseph J. DeGeorge.
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