MARC状态：订购 文献类型：西文图书 浏览次数：3
- 出版发行项:
- Springer 2024.
- ISBN:
- 9783031688102
- 载体形态项:
- 314 p..
- 变异题名:
- 细胞外囊泡基质信使
- 个人责任者:
- Kirsi Rilla.
- 中图法分类号:
- Q2
- 摘要附注:
- The cells in our body release a wide variety of factors into the extracellular space that help to signal, regulate and build the extracellular matrix. One of the most fascinating of these factors are extracellular vesicles (EVs). These lipid membrane-covered particles have now emerged as a new powerful method of near and distant intercellular communication. EVs facilitate communication between cells and their extracellular environment, which includes solid tissues and body fluids. This volume summarizes current knowledge on EVs as integral and active components of the extracellular matrix. It covers topics such as the interplay between EVs and ECM molecules and how cancer cells modify their microenvironment by releasing EVs. Additionally, it discusses how EVs can mediate tissue repair and regeneration by modulating matrix degradation, protein cross-linking, and matrix calcification. The book explores instances where EVs play a crucial role in conditions related to matrix biology, such as cancer and arthritis, and considers their potential as therapeutic agents for these medical conditions.
- 随书光盘:
全部MARC细节信息>>